Santa Cruz Vacations from $314

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Your Santa Cruz Vacation

There's no better way to get away than with one of our vacation packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz vacation is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
45 by Director

45 by Director

3.5 out of 5
Las Condes
per person
Sep 24 - Sep 28
just found
Roundtrip flight included
Buenos Aires (EZE) to Santiago (SCL)
8.8/10 Excellent! (395 reviews)
They told me that I would get a bottle of prosecco with my stay which I didn’t get (there wasn’t in the room where they said it would be. Also because I didn’t have the paper with my entry to the county they wanted to charge me 19% additional taxes. That is not disclosed anywhere.

Reviewed on Jul 3, 2025

Hotel los Españoles Plus

Hotel los Españoles Plus

3.5 out of 5
Providencia
Save 100% on your flight
per person
Sep 24 - Sep 28
just found
Roundtrip flight included
Buenos Aires (EZE) to Santiago (SCL)
9/10 Wonderful! (83 reviews)
Stayed for one night between transport to Argentina. Staff were great, room was big, bed was comfy. Bathroom a little cozy, but fine. Great location for getting around Providencia.

Reviewed on Jan 1, 2025

ICON Hotel

ICON Hotel

4 out of 5
Las Condes
Save 100% on your flight
per person
Sep 24 - Sep 28
found 15 hours ago
Roundtrip flight included
Buenos Aires (EZE) to Santiago (SCL)
8.4/10 Very Good! (1,002 reviews)
The staff was really friendly.

Reviewed on May 29, 2025

Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Providencia
per person
Sep 24 - Sep 28
just found
Roundtrip flight included
Buenos Aires (EZE) to Santiago (SCL)
9/10 Wonderful! (692 reviews)
Clean and big rooms. Plenty of groceries and cafes around. About 20 min walk to Costanera center. Lovely breakfast. Fast internet.

Reviewed on Jun 18, 2025

Hotel Eco Boutique Bidasoa

Hotel Eco Boutique Bidasoa

4 out of 5
Vitacura
Save 100% on your flight
per person
Sep 24 - Sep 28
found 15 hours ago
Roundtrip flight included
Buenos Aires (EZE) to Santiago (SCL)
9.2/10 Wonderful! (216 reviews)
Excellent place with delicious breakfast.

Reviewed on Jun 25, 2025

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Discover the most popular places to visit in Santa Cruz

Lapostolle Clos Apalta Winery

You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Lapostolle Clos Apalta Winery

Casino Colchagua

Why not roll the dice with a visit to Casino Colchagua during your visit to Santa Cruz? While in this relaxing area, you can savor the wineries and restaurants.

Casino Colchagua

Colchagua Campo y Vino

Enjoy an outing to Colchagua Campo y Vino during your stay in Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Colchagua Campo y Vino

What to do in Santa Cruz

Viña Montes

Colchagua Valley Experience

$780
per adult
Colchagua Valley Experience
Viu Manent tour

Viu Manent and Montes Winery, Colchagua Valley from semi-private

$280
per adult
Viu Manent and Montes Winery, Colchagua Valley from semi-private
Santiago Full day tour to Colchahua Valley, include entraces

Santiago Full day tour to Colchahua Valley, include entraces

$390
per adult
Santiago Full day tour to Colchahua Valley, include entraces
See all activities in Santa Cruz

Santa Cruz Hotel Deals

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $121 total per night from Jul 27 to Jul 28
$121 total
Jul 27 - Jul 28
8.6/10 Excellent! (312 reviews)
"The hotel truly shines with its exceptional cleanliness and a refined design that takes inspiration from the Chilean countryside"

Reviewed on Jun 6, 2025

Santa Cruz Plaza
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $89 total per night from Aug 16 to Aug 17
$89 total
Aug 16 - Aug 17
9.4/10 Exceptional! (76 reviews)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service."

Reviewed on Mar 24, 2025

Hotel Vendimia Parador
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
9/10 Wonderful! (95 reviews)
"Nice stay"

Reviewed on Apr 13, 2025

Get rates
La Perla Hotel
See all 52 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Vacation Packages

Santa Cruz Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
33,300
Max Temp Winter
60ºF
Max Temp Summer
90ºF
Top Sights
Lapostolle Clos Apalta Winery, MontGras Winery and Museo de Colchagua

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Frequently asked questions

How much does a Santa Cruz vacation package cost?
You can grab a vacation package to this destination from $314 on Expedia. However, how much your vacation to Santa Cruz costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Cruz?
You can typically find lower prices and greater availability in February, March and November. Explore our cheap Santa Cruz vacation packages and you could score some excellent off-season deals.
How many days is enough for Santa Cruz?
Usually, a handful of days is ideal for a Santa Cruz vacation. With a well-organized itinerary, you can see all the major attractions including Laura Hartwig Winery, as well as discover some hidden gems along the way.
Is it worth booking a vacation package to Santa Cruz?
Whether you're looking to explore key attractions like Museo de Colchagua and Plaza de Armas on your Santa Cruz vacation, or coming for its great history, culture and festivals, there's something for everyone here. With so much to see and do, you'll soon discover why so many people think Santa Cruz is a good vacation destination.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your destination and preferred travel dates under our "Packages" tab. Then add some filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the ideal Santa Cruz package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Cruz escape underway.
Is it cheaper to book a Santa Cruz vacation as a package?
You can enjoy significant savings on your Santa Cruz getaway by booking a tailored vacation package. Check the "Package" heading, then select your destination and travel dates to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Cruz?
Enjoy amazing discounts by booking your flights ahead of time with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for an impromptu Santa Cruz trip.
How to plan a trip to Santa Cruz?

  1. Pick your travel dates: The things you want to do in Santa Cruz and your favorite season will help you decide when to get away.
  2. Plan your budget wisely: On top of the price of your hotel, you should factor in other expenses too. These include flights, transportation and food. Also, put aside some extra funds for unexpected expenses that may arise during your trip to Santa Cruz.
  3. Use Expedia's trip planning tool to discover Santa Cruz: Research every part of your trip to Santa Cruz with this handy planner. Invite family or friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Decide your trip length: Consider how long you want to spend exploring Santa Cruz. Plan your itinerary so you can get to all the activities and attractions you're interested in at a comfortable pace.
  5. Bundle your accommodations and airfare: After you've nailed down your dates and duration, lock in the right Santa Cruz vacation package for you.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best things to do in Santa Cruz and book your tickets in advance to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
If you're anything like us, you love going away but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Santa Cruz break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.