Title: Santa Cruz Vacation Packages 2026 from $312 | Expedia.com [Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d6047957.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d6047957.Travel-Guide-Flights)[Things to do in Santa Cruz](https://expedia.com/Things-To-Do-In-Santa-Cruz.d6047957.Travel-Guide-Activities)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d6047957.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Cruz Vacations from $312 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santa Cruz Vacation There's no better way to get away than with one of our vacation packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like [Lapostolle Clos Apalta Winery](https://www.expedia.com/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Vacation-Attraction), [Laura Hartwig Winery](https://www.expedia.com/Laura-Hartwig-Winery-Santa-Cruz.d553248621532463280.Vacation-Attraction) and [Casino Colchagua](https://www.expedia.com/Casino-Colchagua-Santa-Cruz.d553248621532463282.Vacation-Attraction). Your perfect Santa Cruz vacation is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you. ## The Latest Santa Cruz vacation packages Price found within the past 48 hours. Click for updated prices. ![Hotel Capital Bellet](https://images.trvl-media.com/lodging/28000000/27010000/27000200/27000171/8331c552_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Capital Bellet Providencia $312 per person Apr 24 - Apr 27 found 22 hours ago Roundtrip flight included Buenos Aires (BUE) to Santiago (SCL) 9/10 Wonderful! (988 reviews) Clean, quiet room of adequate size. TV was limited and difficult to work, but not used much. Minimal amenities in the room but adequate. Breakfast great for Chile. Staff available and knowledgable. Reviewed on Mar 20, 2026 ![Hotel Eco Boutique Bidasoa](https://images.trvl-media.com/lodging/2000000/1110000/1103400/1103311/6ac83ffa_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Eco Boutique Bidasoa Vitacura Save 100% on your flight $416 per person May 28 - May 31 found 17 hours ago Roundtrip flight included Buenos Aires (BUE) to Santiago (SCL) 9.4/10 Exceptional! (269 reviews) Beautiful property, nice breakfast buffet, very helpful front desk staff. Walkable neighborhood. Reviewed on Mar 11, 2026 ![ICON Hotel](https://images.trvl-media.com/lodging/18000000/17720000/17714200/17714108/c36f9e94_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### ICON Hotel Las Condes $345 per person Apr 24 - Apr 27 found 22 hours ago Roundtrip flight included Buenos Aires (BUE) to Santiago (SCL) 8.6/10 Excellent! (1,000 reviews) Modern and well located hotel across the street from a subway station. Reviewed on Mar 20, 2026 ![Hotel Director Vitacura](https://images.trvl-media.com/lodging/1000000/30000/27900/27802/bfdfd2bf_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Director Vitacura Vitacura $333 per person Apr 24 - Apr 27 found 22 hours ago Roundtrip flight included Buenos Aires (BUE) to Santiago (SCL) 9/10 Wonderful! (656 reviews) El personal de primer nivel la propiedad necesita mantenerse Reviewed on Mar 22, 2026 ![45 by Director](https://images.trvl-media.com/lodging/1000000/50000/44200/44131/8eca1c48_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### 45 by Director Las Condes $324 per person Apr 24 - Apr 27 found 22 hours ago Roundtrip flight included Buenos Aires (BUE) to Santiago (SCL) 9/10 Wonderful! (467 reviews) Staff was very helpful and room was great! Reviewed on Oct 30, 2025 Don't see what you're looking for? See all available trips from Columbus to Santa Cruz [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-24/2026-05-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SCL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ### Discover the most popular places to visit in Santa Cruz #### Lapostolle Clos Apalta Winery 5/5(3 reviews) You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants. [](https://expedia.com/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Vacation-Attraction) #### Casino Colchagua Why not roll the dice with a visit to Casino Colchagua during your visit to Santa Cruz? While in this relaxing area, you can savor the wineries and restaurants. [](https://expedia.com/Casino-Colchagua-Santa-Cruz.d553248621532463282.Vacation-Attraction) #### Colchagua Campo y Vino 5/5(1 review) Enjoy an outing to Colchagua Campo y Vino during your stay in Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants. [](https://expedia.com/Colchagua-Campo-Y-Vino-Santa-Cruz.d553248621532463281.Vacation-Attraction) ### What to do in Santa Cruz ![Make Your Own Wine & Guided Vineyard Tour ](https://mediaim.expedia.com/localexpert/46200977/2edfdc20-7979-4beb-b97e-2ba00246939c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Make Your Own Wine & Guided Vineyard Tour $46 per adult [](https://expedia.com/things-to-do/make-your-own-wine-guided-vineyard-tour.a46200977.activity-details) ![Viu Manent tour](https://mediaim.expedia.com/localexpert/46790586/8281bde6-a8fc-407d-ba24-3d5b37d230c6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Viu Manent and Montes Winery, Colchagua Valley from semi-private $280 per adult [](https://expedia.com/things-to-do/viu-manent-and-montes-winery.a46790586.activity-details) ![Santiago Full day tour to Colchahua Valley, include entraces](https://mediaim.expedia.com/localexpert/851768/6ac7ea3d-43c1-45ac-91f7-7a704615f25e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santiago Full day tour to Colchahua Valley, include entraces $390 per adult [](https://expedia.com/things-to-do/santiago-full-day-tour-to-colchahua-valley.a851768.activity-details) [See all activities in Santa Cruz](https://expedia.com/things-to-do/search?rid=6047957) ## Santa Cruz Hotel Deals ![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Santa Cruz Plaza Plaza De Armas 286 Santa Cruz O'Higgins $126 nightly $126 total Apr 5 - Apr 6 8.8/10 Excellent! (349 reviews) Me parecio un lindo hotel, el Desayuno es muy completo tipico chileno. Creo que en el chek in deberian informar de las cosas con que cuenta el hotel y paseos, creo que tener que ir a otra oficina es una perdida de recursos. Nos toco una habitacion con tinaja la que disfrutamos es algo muy bueno, ... Reviewed on Mar 20, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=1406642&PinnedHotelID=1406642&HadPinnedHotel=true®ionId=6047957) ![Hotel Cava Colchagua](https://images.trvl-media.com/lodging/10000000/9430000/9423000/9422950/38e10dec_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cava Colchagua Barreales´s Way Santa Cruz O'Higgins $142 nightly $142 total Apr 1 - Apr 2 [](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=9422950&PinnedHotelID=9422950&HadPinnedHotel=true®ionId=6047957) ![Hotel Vendimia Parador](https://images.trvl-media.com/lodging/23000000/22440000/22438600/22438533/93f91da4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Vendimia Parador Camino Los Boldos SN Santa Cruz O'Higgins Fully refundableReserve now, pay when you stay $95 nightly $95 total Mar 25 - Mar 26 9.6/10 Exceptional! (83 reviews) This is a lovely family run establishment in a small traditional building, the interior is delightfully decorated with antique curios. The grounds include a nice pool overlooked by a sun deck which affords views of the surrounding countryside. It also has secure parking. Our room was large and tastefully ... Reviewed on Mar 19, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F25%2F2026&endDate=3%2F26%2F2026&selected=22438533&PinnedHotelID=22438533&HadPinnedHotel=true®ionId=6047957) [See all 56 properties in Santa Cruz](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026®ionId=6047957) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santa Cruz Vacation Packages ### Things to do in Santa Cruz Santa Cruz, located in the O'Higgins Region of Chile, is perfect for romantic getaways and outdoor adventures. Visitors can enjoy hiking trails, skiing, and wine tastings in the area. Day trips and beach vacations are also popular activities, making Santa Cruz an ideal destination for those seeking entertainment and natural beauty. Explore the stunning landscapes and indulge in local wines for a memorable experience. **Shopping** In Santa Cruz, you can explore local markets like the Santa Cruz Craft Fair for unique souvenirs. If you're up for a drive, visit the Plaza de Armas in nearby towns for more shopping options and local artisan crafts that reflect the region's culture. **Recreation** Experience the tranquility of Viña la Playa, featuring rejuvenating spa treatments and yoga sessions amidst beautiful vineyards. For outdoor enthusiasts, explore the scenic hiking trails of the Colchagua Valley, where you can enjoy nature and stunning landscapes while unwinding in the serene atmosphere of Santa Cruz. **Adventure** Explore the breathtaking landscapes of the Colchagua Valley through exhilarating mountain biking tours. Experience wine tasting at renowned vineyards, where you can savor local flavors. For a thrill, try horseback riding through picturesque trails that showcase the region's natural beauty and rich culture. **Nightlife** Santa Cruz offers a vibrant nightlife with lively bars and cozy venues. Enjoy local wines at the charming La Casona del Vino or dance the night away at the popular Club Santa Cruz. For a relaxed vibe, unwind at Café de la Plaza while soaking in the local atmosphere. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Find the best attractions in Santa Cruz Santa Cruz, in the O'Higgins Region of Chile, offers a delightful blend of romance, entertainment, and outdoor adventures. Explore its charming attractions, vibrant piazzas, and rich history museums that provide a taste of local culture and city life. Don't miss out on optional activities like visiting Santa Cruz County, the beach, or nearby Santa Barbara to make your vacation even more memorable. - **[Colchagua Campo y Vino: ](https://www.expedia.com/Colchagua-Campo-Y-Vino-Santa-Cruz.d553248621532463281.Vacation-Attraction)** Experience the serene beauty of the Colchagua Valley at this luxury attraction, where you can indulge in relaxing excursions among vineyards. Taste exquisite wines and enjoy the breathtaking landscapes that define this renowned wine region. - **[Museo de Colchagua: ](https://www.expedia.com/Museo-De-Colchagua-Santa-Cruz.d6099456.Vacation-Attraction)** Dive into the rich cultural heritage of Chile at this history museum. With its extensive collections of artifacts and exhibits, you'll gain insight into the region's historical significance and the traditions that shape its identity. - **Plaza de Armas:** The heart of Santa Cruz, this vibrant square is perfect for soaking up local culture. Enjoy leisurely strolls, admire historical architecture, and immerse yourself in the lively atmosphere, making it a great spot for people-watching and relaxation. ### Best time to go to Santa Cruz The best time to visit Santa Cruz can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Cruz falls in January, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature in Santa Cruz falls in July, visitor numbers are average and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 72.5°F (22.5°C) | No Rain | Sunny | Slightly High | Average | | February | 71.6°F (22.0°C) | No Rain | Sunny | Slightly High | Average | | March | 68.4°F (20.2°C) | No Rain | Sunny | Slightly High | Slightly Low | | April | 61.5°F (16.4°C) | No Rain | Sunny | Average | Slightly High | | May | 55.2°F (12.9°C) | Light Rain | Mostly Sunny | Slightly Low | Slightly High | | June | 49.6°F (9.8°C) | Light Rain | Mostly Sunny | Average | Average | | July | 47.5°F (8.6°C) | Light Rain | Mostly Sunny | Average | Average | | August | 50.0°F (10.0°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | September | 53.2°F (11.8°C) | Light Rain | Mostly Sunny | Average | Average | | October | 57.9°F (14.4°C) | No Rain | Sunny | Slightly Low | Slightly High | | November | 64.6°F (18.1°C) | No Rain | Sunny | Slightly Low | Average | | December | 69.3°F (20.7°C) | No Rain | Sunny | Average | Slightly Low | ### Tips to save on your trip to Santa Cruz - Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Cruz. - Consider traveling during the off-peak season (typically March, August and December) for more affordable package holidays to Santa Cruz. - Use the *Price per traveler* filter on Expedia to find a package deal that suits your budget. - Check the *VIP Access properties* filter to discover outstanding hotels with added member perks at select properties. ## Santa Cruz Essential Information | Language | Spanish | | --------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Chilean pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 33,300 | | Max Temp Winter | 60ºF | | Max Temp Summer | 90ºF | | Top Sights | [Lapostolle Clos Apalta Winery](https://www.expedia.com/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Vacation-Attraction), [MontGras Winery](https://www.expedia.com/MontGras-Winery-Palmilla.d6283554.Vacation-Attraction) and [Museo de Colchagua](https://www.expedia.com/Museo-De-Colchagua-Santa-Cruz.d6099456.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a Santa Cruz vacation package cost? ### What are the cheapest months to go to Santa Cruz? ### How many days is enough for Santa Cruz? ### Is it worth booking a vacation package to Santa Cruz? ### How to find the best Santa Cruz package deals? ### Is it cheaper to book a Santa Cruz vacation as a package? ### When to book a vacation package to Santa Cruz? ### How to plan a trip to Santa Cruz? > 1. Pick your travel dates: The things you want to do in Santa Cruz and your favorite season will help you decide when to get away. > 2. Plan your budget wisely: On top of the price of your hotel, you should factor in other expenses too. These include flights, transportation and food. Also, put aside some extra funds for unexpected expenses that may arise during your trip to Santa Cruz. > 3. Use Expedia's [trip planning tool](https://www.expedia.com/why/trip-planning) to discover Santa Cruz: Research every part of your trip to Santa Cruz with this handy planner. Invite family or friends to collaborate on a group trip, search for hotels or things to do and make bookings. > 4. Decide your trip length: Consider how long you want to spend exploring Santa Cruz. Plan your itinerary so you can get to all the activities and attractions you're interested in at a comfortable pace. > 5. Bundle your accommodations and airfare: After you've nailed down your dates and duration, lock in the right Santa Cruz vacation package for you. > 6. Book any excursions or activities: Now to the fun part — locking in everything you want to see and do. Explore some of the best [things to do in Santa Cruz](https://www.expedia.com/Things-To-Do-In-Santa-Cruz.d6047957.Travel-Guide-Activities) and book your tickets in advance to save time (and maybe some money too!). ### Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - More ways to book - [Hotels near Plaza de Armas ](https://www.expedia.com/Plaza-De-Armas-Hotels.0-l6099454-0.Travel-Guide-Filter-Hotels) - [Hotels near Laura Hartwig Winery ](https://www.expedia.com/Laura-Hartwig-Winery-Hotels.0-l553248621532463280-0.Travel-Guide-Filter-Hotels) - [Cunaco Hotels ](https://www.expedia.com/Cunaco-Hotels.d3000006419.Travel-Guide-Hotels) - [Hotels near Lapostolle Clos Apalta Winery ](https://www.expedia.com/Lapostolle-Clos-Apalta-Winery-Hotels.0-l553248621532463283-0.Travel-Guide-Filter-Hotels) - [Winery Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Winery-Hotel.0-0-d3000655744-tWineryHotel.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/5Star-Colchagua-Valley-Wine-Route-Hotels.s50-0-d3000655744.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Cabins.d3000655744-aaCabins.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Pet-Friendly-Hotel.0-0-d3000655744-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Colchagua Valley Wine Route Hotels ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels.d3000655744.Travel-Guide-Hotels) - [Hotels with Restaurants in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Hotels-With-Restaurants.0-0-d3000655744-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Spa-Hotel.0-0-d3000655744-tSpaHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Luxury-Hotel.0-0-d3000655744-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Wedding-Hotels.0-0-d3000655744-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels-Golf-Hotel.0-0-d3000655744-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels near MontGras Winery ](https://www.expedia.com/MontGras-Winery-Hotels.0-l6283554-0.Travel-Guide-Filter-Hotels) - [Palmilla Hotels ](https://www.expedia.com/Palmilla-Hotels.d6285090.Travel-Guide-Hotels) - [Peralillo Hotels ](https://www.expedia.com/Peralillo-Hotels.d3000006320.Travel-Guide-Hotels) - [Hotels near Viña Escondida ](https://www.expedia.com/Vina-Escondida-Hotels.0-l553248635975257805-0.Travel-Guide-Filter-Hotels) - [Hotels near Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Hotels.0-l553248621532463279-0.Travel-Guide-Filter-Hotels) - [Lolol Hotels ](https://www.expedia.com/Lolol-Hotels.d3000006362.Travel-Guide-Hotels) - [B&B in Lolol ](https://www.expedia.com/Lolol-Bed-And-Breakfast.d3000006362-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Chimbarongo Hotels ](https://www.expedia.com/Chimbarongo-Hotels.d6354855.Travel-Guide-Hotels) - [San Vicente Hotels ](https://www.expedia.com/San-Vicente-Hotels.d6338195.Travel-Guide-Hotels) - [Resorts & Hotels with Spas in San Vicente ](https://www.expedia.com/San-Vicente-Hotels-Spa-Hotel.0-0-d6338195-tSpaHotel.Travel-Guide-Filter-Hotels) - [Peumo Hotels ](https://www.expedia.com/Peumo-Hotels.d553248635942910167.Travel-Guide-Hotels) - [All-Inclusive Resorts in O'Higgins Region ](https://www.expedia.com/Destinations-In-OHiggins-Region-All-Inclusive-Hotel.0-0-d6236498-tAllinclusiveHotel.Hotel-Filter-Destinations) - [Family Hotels in O'Higgins Region ](https://www.expedia.com/Destinations-In-OHiggins-Region-Family-Hotel.0-0-d6236498-tFamilyHotel.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in O'Higgins Region ](https://www.expedia.com/Destinations-In-OHiggins-Region-Spa-Hotel.0-0-d6236498-tSpaHotel.Hotel-Filter-Destinations) - [Golf Hotels in O'Higgins Region ](https://www.expedia.com/Destinations-In-OHiggins-Region-Golf-Hotel.0-0-d6236498-tGolfHotel.Hotel-Filter-Destinations) - [Hotels near TreMonte Winery / Vina TreMonte ](https://www.expedia.com/TreMonte-Winery-Vina-TreMonte-Hotels.0-l553248621532463284-0.Travel-Guide-Filter-Hotels) - [Hotels near San Vicente Square ](https://www.expedia.com/San-Vicente-Square-Hotels.0-l553248621558085385-0.Travel-Guide-Filter-Hotels) - [Hotels near Iglesia de San Francisco ](https://www.expedia.com/Iglesia-De-San-Francisco-Hotels.0-l6099452-0.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotels-With-Hot-Tubs.0-0-d6053655-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [All-Inclusive Resorts in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-All-Inclusive-Hotel.0-0-d6053655-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Romantic-Hotel.0-0-d6053655-tRomanticHotel.Travel-Guide-Filter-Hotels) - [San Fernando Hotels ](https://www.expedia.com/San-Fernando-Hotels.d6053655.Travel-Guide-Hotels) - [Pet-Friendly Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Pet-Friendly-Hotel.0-0-d6053655-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Spa-Hotel.0-0-d6053655-tSpaHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Boutique-Hotel.0-0-d6053655-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [B&B in San Fernando ](https://www.expedia.com/San-Fernando-Bed-And-Breakfast.d6053655-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Winery Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Winery-Hotel.0-0-d6053655-tWineryHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotels-With-Indoor-Pool.0-0-d6053655-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Historic Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Historic-Hotel.0-0-d6053655-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Casino-Hotel.0-0-d6053655-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Beach Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Beach-Hotel.0-0-d6053655-tBeachHotel.Travel-Guide-Filter-Hotels) - [Family Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Family-Hotel.0-0-d6053655-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Wedding-Hotels.0-0-d6053655-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Parking in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotels-With-Free-Parking.0-0-d6053655-tHotelswithFreeParking.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Luxury-Hotel.0-0-d6053655-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Hotels with Bars in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Bar-Hotel.0-0-d6053655-tBarHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotel-With-Pool.0-0-d6053655-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Facilities in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotels-With-Laundry-Facilities.0-0-d6053655-tHotelswithLaundryFacilities.Travel-Guide-Filter-Hotels) - [Golf Hotels in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Golf-Hotel.0-0-d6053655-tGolfHotel.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d6053655-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts & in San Fernando ](https://www.expedia.com/San-Fernando-Hotels-Honeymoon-Hotels.0-0-d6053655-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Lodges in San Fernando ](https://www.expedia.com/San-Fernando-Lodges.d6053655-aaLodges.Travel-Guide-Accommodation) - [Las Cabras Hotels ](https://www.expedia.com/Las-Cabras-Hotels.d3000006372.Travel-Guide-Hotels) - [Cabin Rentals in Marchihue ](https://www.expedia.com/Marchihue-Cabins.d6176398-aaCabins.Travel-Guide-Accommodation) - [Flights to Colchagua Valley Wine Route ](https://www.expedia.com/Cheap-Flights-To-Colchagua-Valley-Wine-Route.d3000655744.Travel-Guide-Flights) - [Flights to Palmilla ](https://www.expedia.com/Cheap-Flights-To-Palmilla.d6285090.Travel-Guide-Flights) - [Flights to O'Higgins Region ](https://www.expedia.com/Destinations-In-OHiggins-Region.d6236498.Flight-Destinations) - [Flights from O'Higgins Region ](https://www.expedia.com/lp/flights/6236498/flights-from-ohiggins-region) - [Flights to San Fernando ](https://www.expedia.com/Cheap-Flights-To-San-Fernando.d6053655.Travel-Guide-Flights) - [Museo de Colchagua ](https://www.expedia.com/Museo-De-Colchagua-Santa-Cruz.d6099456.Vacation-Attraction) - [Visit Cunaco ](https://www.expedia.com/Cunaco.dx3000006419) - [Lapostolle Clos Apalta Winery ](https://www.expedia.com/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Vacation-Attraction) - [Colchagua Valley Wine Route Vacations ](https://www.expedia.com/Colchagua-Valley-Wine-Route.d3000655744.Destination-Travel-Guides) - [Montgras Winery ](https://www.expedia.com/MontGras-Winery-Palmilla.d6283554.Vacation-Attraction) - [Visit Colchagua Valley Wine Route ](https://www.expedia.com/Colchagua-Valley-Wine-Route.dx3000655744) - [Hacienda El Huique ](https://www.expedia.com/Hacienda-El-Huique-Palmilla.d6099458.Vacation-Attraction) - [Visit Palmilla ](https://www.expedia.com/Palmilla.dx6285090) - [Nancagua Vacations ](https://www.expedia.com/Nancagua.d3000006338.Destination-Travel-Guides) - [Visit Nancagua ](https://www.expedia.com/Nancagua.dx3000006338) - [Colchagua Automobile Museum ](https://www.expedia.com/Colchagua-Automobile-Museum-Lolol.d553248635997986367.Vacation-Attraction) - [Visit Peralillo ](https://www.expedia.com/Peralillo.dx3000006320) - [Visit Placilla ](https://www.expedia.com/Placilla.dx3000006313) - [Viña Escondida ](https://www.expedia.com/Vina-Escondida-Placilla.d553248635975257805.Vacation-Attraction) - [Millahue Valley ](https://www.expedia.com/Millahue-Valley-San-Vicente.d553248635976913024.Vacation-Attraction) - [Lolol Vacations ](https://www.expedia.com/Lolol.d3000006362.Destination-Travel-Guides) - [Visit Lolol ](https://www.expedia.com/Lolol.dx3000006362) - [Visit Chimbarongo ](https://www.expedia.com/Chimbarongo.dx6354855) - [Visit Pichidegua ](https://www.expedia.com/Pichidegua.dx6360683) - [Visit Peumo ](https://www.expedia.com/Peumo.dx553248635942910167) - [Plaza de San Fernando ](https://www.expedia.com/Plaza-De-San-Fernando-San-Fernando.d6099450.Vacation-Attraction) - [San Fernando Vacations ](https://www.expedia.com/San-Fernando.d6053655.Destination-Travel-Guides) - [Visit San Fernando ](https://www.expedia.com/San-Fernando.dx6053655) - [Visit Las Cabras ](https://www.expedia.com/Las-Cabras.dx3000006372) - [Visit Marchihue ](https://www.expedia.com/Marchihue.dx6176398) - [Car rentals near Palmilla ](https://www.expedia.com/Car-Rentals-In-Palmilla.d6285090.Car-Rental-Guide) - [Car rentals near Peralillo ](https://www.expedia.com/Car-Rentals-In-Peralillo.d3000006320.Car-Rental-Guide) - [Car rentals near Colchagua Valley Wine Route ](https://www.expedia.com/Car-Rentals-In-Colchagua-Valley-Wine-Route.d553248621532463279.Car-Rental-Guide) - [Car rentals near Pumanque ](https://www.expedia.com/Car-Rentals-In-Pumanque.d553248635943692202.Car-Rental-Guide) - [Car rentals near Chimbarongo ](https://www.expedia.com/Car-Rentals-In-Chimbarongo.d6354855.Car-Rental-Guide) - [Car rentals near San Vicente ](https://www.expedia.com/Car-Rentals-In-San-Vicente.d6338195.Car-Rental-Guide) - [Car rentals near San Fernando ](https://www.expedia.com/Car-Rentals-In-San-Fernando.d6053655.Car-Rental-Guide) - [Car rentals near Las Cabras ](https://www.expedia.com/Car-Rentals-In-Las-Cabras.d3000006372.Car-Rental-Guide) - [Colchagua Valley Wine Route Vacation Rentals ](https://www.expedia.com/Colchagua-Valley-Wine-Route-Vacation-Rentals.d3000655744.Travel-Guide-VacationRentals) - [San Fernando Vacation Rentals ](https://www.expedia.com/San-Fernando-Vacation-Rentals.d6053655.Travel-Guide-VacationRentals) - [Things to do in O'Higgins Region ](https://www.expedia.com/Things-To-Do-In-OHiggins-Region.d6236498.Travel-Guide-Activities) - [Things to do in San Fernando ](https://www.expedia.com/Things-To-Do-In-San-Fernando.d6053655.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app